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. 1994;72(5):783–796.

Poliomyelitis control in Israel, the West Bank and Gaza Strip: changing strategies with the goal of eradication in an endemic area.

N Goldblum 1, C B Gerichter 1, T H Tulchinsky 1, J L Melnick 1
PMCID: PMC2486552  PMID: 7955030

Abstract

Israel has faced the challenge presented by epidemic poliomyelitis by using different immunization strategies. In the 1950s, inactivated poliovirus vaccine (IPV) helped to reduce the total burden of the disease, but cases continued to occur. Introduction of oral poliovirus vaccine (OPV) in mid-1961 had a dramatic effect in controlling an extensive epidemic of poliomyelitis; however, poliovirus activity and cases continued during the 1970s, and at a low level in the 1980s. A localized outbreak of 15 cases of poliomyelitis in 1988 occurred in an area using enhanced potency IPV (eIPV) only. This led to a revision of poliomyelitis immunization policy. The successful poliomyelitis control in the West Bank and the Gaza Strip using both OPV and IPV since 1978 shows the advantages of a combined approach. This programme was therefore adopted in modified form in the whole of Israel, the West Bank and Gaza. Since late 1988, no cases of poliomyelitis have occurred in any of these three areas, indicating the success of the combined poliomyelitis immunization programme. These experiences may be helpful to other countries, especially those where there is a danger of importation of wild poliovirus, and to prevent vaccine-associated disease. The combined approach provides an additional immunization model in the international effort to eradicate poliomyelitis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Böthig B., Danes L., Dittmann S. Immunogenicity of oral poliomyelitis vaccine (OPV) against variants of wild poliovirus type 3. Bull World Health Organ. 1990;68(5):597–600. [PMC free article] [PubMed] [Google Scholar]
  2. Böttiger M. Long-term immunity following vaccination with killed poliovirus vaccine in Sweden, a country with no circulating poliovirus. Rev Infect Dis. 1984 May-Jun;6 (Suppl 2):S548–S551. doi: 10.1093/clinids/6.supplement_2.s548. [DOI] [PubMed] [Google Scholar]
  3. DAVIES A. M., MARBERG K., GOLDBLUM N., LEVINE S., YEKUTIEL P. Epidemiology of poliomyelitis in Israel, 1952-59, with evaluation of Salk vaccination during a three-year period. Bull World Health Organ. 1960;23:53–72. [PMC free article] [PubMed] [Google Scholar]
  4. De Quadros C. A., Andrus J. K., Olivé J. M., Da Silveira C. M., Eikhof R. M., Carrasco P., Fitzsimmons J. W., Pinheiro F. P. Eradication of poliomyelitis: progress in the Americas. Pediatr Infect Dis J. 1991 Mar;10(3):222–229. doi: 10.1097/00006454-199103000-00011. [DOI] [PubMed] [Google Scholar]
  5. Deivanayagam N., Nedunchelian K., Ahamed S. S., Rathnam S. R. Clinical efficacy of trivalent oral poliomyelitis vaccine: a case-control study. Bull World Health Organ. 1993;71(3-4):307–309. [PMC free article] [PubMed] [Google Scholar]
  6. GOLDBLUM N., GITER S. [Poliomyelitis vaccines]. Harefuah. 1961 Jun 15;60:405–406. [PubMed] [Google Scholar]
  7. GOLDBLUM N., YOFE Y., EYLAN E. POLIOMYELITIS IN ISRAEL, 1949 TO 1963, AND THE RECENT USE OF ATTENUATED POLIOMYELITIS VACCINES IN ITS CONTROL. Isr J Med Sci. 1965 Mar;1:235–242. [PubMed] [Google Scholar]
  8. Goldblum N., Swartz T. The Israeli experience in the control of poliomyelitis during a quarter of a century, 1957-1982. Rev Infect Dis. 1984 May-Jun;6 (Suppl 2):S313–S317. doi: 10.1093/clinids/6.supplement_2.s313. [DOI] [PubMed] [Google Scholar]
  9. Green M. S., Cohen D., Slepon R., Handsher R., Zaaide Y., Rannon L., Danon Y. Sociodemographic correlates of neutralizing poliovirus and hepatitis A virus antibodies as markers of different modes of acquiring immunity. Am J Public Health. 1990 Oct;80(10):1270–1271. doi: 10.2105/ajph.80.10.1270. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Green M. S., Handsher R., Cohen D., Melnick J. L., Slepon R., Mendelsohn E., Danon Y. L. Age differences in immunity against wild and vaccine strains of poliovirus prior to the 1988 outbreak in Israel and response to booster immunization. Vaccine. 1993;11(1):75–81. doi: 10.1016/0264-410x(93)90342-u. [DOI] [PubMed] [Google Scholar]
  11. Hovi T., Cantell K., Huovilainen A., Kinnunen E., Kuronen T., Lapinleimu K., Pöyry T., Roivainen M., Salama N., Stenvik M. Outbreak of paralytic poliomyelitis in Finland: widespread circulation of antigenically altered poliovirus type 3 in a vaccinated population. Lancet. 1986 Jun 21;1(8495):1427–1432. doi: 10.1016/s0140-6736(86)91566-7. [DOI] [PubMed] [Google Scholar]
  12. Kim-Farley R. J., Rutherford G., Lichfield P., Hsu S. T., Orenstein W. A., Schonberger L. B., Bart K. J., Lui K. J., Lin C. C. Outbreak of paralytic poliomyelitis, Taiwan. Lancet. 1984 Dec 8;2(8415):1322–1324. doi: 10.1016/s0140-6736(84)90831-6. [DOI] [PubMed] [Google Scholar]
  13. LEVINE S., GOLDBLUM N., FRIEDMAN E. Virologic findings and antibody response of newborns fed multiple type oral poliomyelitis vaccine. Am J Hyg. 1961 Jul;74:95–103. doi: 10.1093/oxfordjournals.aje.a120204. [DOI] [PubMed] [Google Scholar]
  14. Lasch E. E., Abed Y., Abdulla K., El Tibbi A. G., Marcus O., El Massri M., Handscher R., Gerichter C. B., Melnick J. L. Successful results of a program combining live and inactivated poliovirus vaccines to control poliomyelitis in Gaza. Rev Infect Dis. 1984 May-Jun;6 (Suppl 2):S467–S470. doi: 10.1093/clinids/6.supplement_2.s467. [DOI] [PubMed] [Google Scholar]
  15. Lasch E. E., Abed Y., Gerichter C. B., Massri M. E., Marcus O., Hensher R., Goldblum N. Results of a program successfully combining live and killed polio vaccines. Isr J Med Sci. 1983 Nov;19(11):1021–1023. [PubMed] [Google Scholar]
  16. Lasch E. E., Abed Y., Marcus O., Gerichter C. B., Melnick J. L. Combined live and inactivated poliovirus vaccine to control poliomyelitis in a developing country--five years after. Dev Biol Stand. 1986;65:137–143. [PubMed] [Google Scholar]
  17. Leads from the MMWR. Poliomyelitis prevention: enhanced-potency inactivated poliomyelitis vaccine--supplementary statement. JAMA. 1988 Jan 15;259(3):345–346. [PubMed] [Google Scholar]
  18. MERCADO A., GOLDBLUM N. [On the immunogenic activity of poliomyelitis vaccines (Salk type)]. Harefuah. 1959 Feb 15;56(4):93–96. [PubMed] [Google Scholar]
  19. Melnick J. L. Combined use of live and killed vaccines to control poliomyelitis in tropical areas. Dev Biol Stand. 1981;47:265–273. [PubMed] [Google Scholar]
  20. Melnick J. L. Poliomyelitis: eradication in sight. Epidemiol Infect. 1992 Feb;108(1):1–18. doi: 10.1017/s0950268800049451. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Nkowane B. M., Wassilak S. G., Orenstein W. A., Bart K. J., Schonberger L. B., Hinman A. R., Kew O. M. Vaccine-associated paralytic poliomyelitis. United States: 1973 through 1984. JAMA. 1987 Mar 13;257(10):1335–1340. [PubMed] [Google Scholar]
  22. Slater P. E., Orenstein W. A., Morag A., Avni A., Handsher R., Green M. S., Costin C., Yarrow A., Rishpon S., Havkin O. Poliomyelitis outbreak in Israel in 1988: a report with two commentaries. Lancet. 1990 May 19;335(8699):1192–1198. doi: 10.1016/0140-6736(90)92705-m. [DOI] [PubMed] [Google Scholar]
  23. Sutter R. W., Patriarca P. A., Brogan S., Malankar P. G., Pallansch M. A., Kew O. M., Bass A. G., Cochi S. L., Alexander J. P., Hall D. B. Outbreak of paralytic poliomyelitis in Oman: evidence for widespread transmission among fully vaccinated children. Lancet. 1991 Sep 21;338(8769):715–720. doi: 10.1016/0140-6736(91)91442-w. [DOI] [PubMed] [Google Scholar]
  24. Swartz T. A., Ben-Porath E., Kanaaneh H., Leitner L., Goldblum N. Comparison of inactivated poliovirus vaccine and oral poliovirus vaccine programs in Israel. Rev Infect Dis. 1984 May-Jun;6 (Suppl 2):S556–S561. doi: 10.1093/clinids/6.supplement_2.s556. [DOI] [PubMed] [Google Scholar]
  25. Tulchinsky T., Abed Y., Shaheen S., Toubassi N., Sever Y., Schoenbaum M., Handsher R. A ten-year experience in control of poliomyelitis through a combination of live and killed vaccines in two developing areas. Am J Public Health. 1989 Dec;79(12):1648–1652. doi: 10.2105/ajph.79.12.1648. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. YEKUTIEL P., LEVINGER E. L., MUHSAM H. V., YEKUTIEL M. P. Poliomyelitis outbreak in Israel, 1950-1. Bull World Health Organ. 1955;12(4):651–676. [PMC free article] [PubMed] [Google Scholar]
  27. YEKUTIEL P., MARBERG K., GOLDBLUM N., LEVINE S. [Results of immunization against poliomyelitis in Israel during 1957]. Harefuah. 1958 May 1;54(9):225-6; English & French abstracts, 226. [PubMed] [Google Scholar]
  28. YOFE J., GOLDBLUM N., EYLAN E., MELNICK J. L. An outbreak of poliomyelitis in Israel in 1961 and the use of attenuated type 1 vaccine in its control. Am J Hyg. 1962 Nov;76:225–238. doi: 10.1093/oxfordjournals.aje.a120278. [DOI] [PubMed] [Google Scholar]
  29. von Magnus H., Petersen I. Vaccination with inactivated poliovirus vaccine and oral poliovirus vaccine in Denmark. Rev Infect Dis. 1984 May-Jun;6 (Suppl 2):S471–S474. doi: 10.1093/clinids/6.supplement_2.s471. [DOI] [PubMed] [Google Scholar]

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