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. 2018 May 2;98(3):1169–1203. doi: 10.1152/physrev.00023.2017

FIGURE 20.

FIGURE 20.

SNPs in the NRF2 promoter and AREs. SNPs in the NRF2 promoter alter the transcription level of the NRF2 gene. SNPs in AREs alter the binding affinity of NRF2-sMAF heterodimers and transcription levels of NRF2 target genes.