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Extended Data Fig. 10

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Relationship between radiology and pathology and other clinical/biomarker correlates.

a, Patients with LN involvement by imaging at baseline and by pathology at resection by treatment arm. b, Radiographic (BOR per RECIST1.1) and pathologic response (%RVT) in PT. c, Radiographic (BOR per RECIST1.1) and pathologic response (%RVT) in LN, across treatment arms. d, Radiographic (BOR per RECIST1.1) and pathologic response (%RVT) in LN by treatment arm. e, ctDNA clearance and pathologic response (%RVT) in PT. f, ctDNA clearance and pathologic response (%RVT) in LN, across treatment arms. g, ctDNA clearance and pathologic response (%RVT) in LN by treatment arm. BOR denotes best overall response; CR complete response; LN, lymph node; MPR, major pathologic response; NE, not evaluable; pCR, pathologic complete response; PD, progressive disease; PR, partial response; PT, primary tumor; RECIST1.1, Response Evaluation Criteria in Solid Tumors version 1.1; RVT, residual viable tumor; SD, stable disease. aData were not reported for 1 patient. bctDNA data were not available/not evaluable for 108 patients. cctDNA data were not available/not evaluable for 93 patients. dctDNA data were not available/not evaluable for 109 patients. ectDNA data were not available/not evaluable for 53 patients. fctDNA data were not available/not evaluable for 56 patients.

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