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A cellular reference atlas across human brain regions

We present the Brain Cell Atlas, integrating single-cell transcriptomes of 26 million cells from 70 human and 103 mouse studies, covering 14 major brain regions. This atlas takes advantage of the integration of big data, enabling the discovery of putative neural progenitors in adults and microglial regional variations.

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Fig. 1: Identification of putative neural progenitors and microglia subtypes.

References

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This is a summary of: Chen, X. et al. A brain cell atlas integrating single-cell transcriptomes across human brain regions. Nat. Med. https://doi.org/10.1038/s41591-024-03150-z (2024).

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A cellular reference atlas across human brain regions. Nat Med 30, 2421–2422 (2024). https://doi.org/10.1038/s41591-024-03151-y

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