Apoptosis shapes T cell development and immune responses. The pro-apoptotic molecules Bax and Bak have overlapping essential functions in T cell development and homeostasis.
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References
Strasser, A., Harris, A.W., Huang, D.C.S., Krammer, P.H. & Cory, S. EMBO J. 14, 6136–6147 (1995).
Lindsten, T. et al. Mol. Cell 6, 1389–1399 (2000).
Rathmell, J.C., Lindsten, T., Zong, W.-X., Cinalli, R.M. & Thompson, C.B. Nature Immunol. 3, 932–939 (2002).
Strasser, A., Harris, A.W., Corcoran, L.M. & Cory, S. Nature 368, 457–460 (1994).
Linette, G.P. et al. Immunity 1, 197–205 (1994).
Bouillet, P. et al. Science 286, 1735–1738 (1999).
Bouillet, P. et al. Nature 415, 922–926 (2002).
Hildeman, D.A. et al. Immunity 16, 759–767 (2002).
Huang, D.C.S. & Strasser, A. Cell 103, 839–842 (2000).
Zong, W.X., Lindsten, T., Ross, A.J., MacGregor, G.R. & Thompson, C.B. Genes Dev. 15, 1481–1486 (2001).
Cheng, E.H. et al. Mol. Cell 8, 705–711 (2001).
Strasser, A., Harris, A.W., Bath, M.L. & Cory, S. Nature 348, 331–333 (1990).
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Bouillet, P., Strasser, A. Bax and Bak: back-bone of T cell death. Nat Immunol 3, 893–894 (2002). https://doi.org/10.1038/ni1002-893
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DOI: https://doi.org/10.1038/ni1002-893
