Abstract
Micro RNAs are a large family of noncoding RNAs of 21–22 nucleotides whose functions are generally unknown. Here a large subset of Drosophila micro RNAs is shown to be perfectly complementary to several classes of sequence motif previously demonstrated to mediate negative post-transcriptional regulation. These findings suggest a more general role for micro RNAs in gene regulation through the formation of RNA duplexes.
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Acknowledgements
E.C.L. is supported by Gerald Rubin and by the Cancer Research Fund of the Damon Runyon-Walter Winchell Foundation.
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Lai, E. Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation. Nat Genet 30, 363–364 (2002). https://doi.org/10.1038/ng865
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DOI: https://doi.org/10.1038/ng865
