Cells sense and respond to physical stresses through mechanotransduction, a process that converts mechanical stimuli into biochemical signals. The bending of primary cilia has now been shown to modulate TOR signalling to negatively regulate cell size.
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Wiczer, B., Kalender, A. & Thomas, G. Bending the path to TOR. Nat Cell Biol 12, 1031–1033 (2010). https://doi.org/10.1038/ncb1110-1031
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DOI: https://doi.org/10.1038/ncb1110-1031
