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A phylogeny is a hypothetical reconstruction of the evolutionary relationships of a group of organisms or a set of sequences (nucleotide or amino acid). Phylogenies are often represented graphically in the form of a 'tree' and enable scientists to find new relationships between organisms.
This work presents CalicoST for inferring allele-specific copy numbers and reconstructing spatial tumor evolution by using spatial transcriptomics data.
Here, the authors produce an updated termite classification with genomic scale analyses, highlighting thirteen family-level lineages and resilience of their classification to future termite research.
The evolution of sperm length remains an elusive topic. This study applies the Pareto multi-task evolution framework to investigate sperm length variation in relation to body mass across tetrapods and find that sperm length evolution is mainly driven by sperm competition and clutch size.
Using SARS-CoV-2 viral genome data, Goliaei et al analyze the changes in SARS-CoV-2 lineage importation into Germany after implementation of different nonpharmaceutical interventions in late 2020 and early 2021, and observe large declines after introduction of free rapid tests, and stronger regulations on mask-wearing, as well as on internal movements and gatherings.
The concept of reference frames inspires researchers to develop a differential ranking system for measuring relative differential abundance, which does not require information about absolute microbial load.
