Extended Data Fig. 5: The transcription and protein expression levels for SPP1 and myelin-specific genes. | Nature Medicine

Extended Data Fig. 5: The transcription and protein expression levels for SPP1 and myelin-specific genes.

From: A brain cell atlas integrating single-cell transcriptomes across human brain regions

Extended Data Fig. 5

a. UMAP plots show the expression of SPP1 and myelin proteins (MBP, MAG, and MOG) in microglia (PCDH9high). b. Triple immunostaining of SPP1 (red), PCDH9 (grey), and MAG (green) confirmed the phagocytosis of myelin debris by microglia (PCDH9high) in the cornu ammonis of the hippocampus (n = 1 specimen). Scale bars, 20 μm (overview) and 10 μm (magnification).

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