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Role of Thymus-derived Lymphocytes in the Secondary Humoral Immune Response in Mice

Nature volume 226, pages 1257–1258 (1970)Cite this article

Abstract

THERE is now good evidence that the theta (θ) isoantigen of mice1 is carried only by those peripheral lymphocytes which are thymus-derived2–4, so that anti-θ antiserum should be useful in elucidating the role of these cells in immunity. In experiments reported here, anti-θ has been used in vitro in an adoptive transfer system5 to study the function of thymus-derived lymphocytes in the secondary humoral immune response to hapten–protein conjugates, particularly in terms of cellular cooperation and carrier effects.

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  1. National Institute for Medical Research, Mill Hill, London, NW7

    MARTIN C. RAFF

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  1. MARTIN C. RAFF
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RAFF, M. Role of Thymus-derived Lymphocytes in the Secondary Humoral Immune Response in Mice. Nature 226, 1257–1258 (1970). https://doi.org/10.1038/2261257a0

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