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Getting to MD Anderson

The MD Anderson Directions app offers customized driving directions to every MD Anderson location, as well as walking directions between locations on campus.

Below are:

Basic driving directions to MD Anderson from major Houston highways.
Information about numbered entry markers. These can help identify the best entrance to use to bring a patient, self-park or valet park.

Driving directions

Traveling south from Bush Intercontinental Airport / U.S. 59

Take Will Clayton Boulevard east to U.S. 59
Turn right (south) on U.S. 59 and follow it to Texas 288
Exit onto Texas 288 and follow it south to the N. MacGregor exit
Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard
Continue heading straight, onto Braeswood, as N. MacGregor bears right
Follow Braeswood to Holcombe Boulevard
Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker

Traveling south from Hardy Toll Road

Take Hardy Toll Road south to Interstate 610 east
Follow I-610 East and exit onto U.S. 59 South
From U.S. 59 exit onto Texas 288 and follow it south to the N. MacGregor exit
Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard
Continue heading straight, onto Braeswood, as N. MacGregor bears right
Follow Braeswood to Holcombe Boulevard
Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker

Traveling north from U.S. 59

Exit onto Texas 288 and follow it south to the N. MacGregor exit
Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard
Continue heading straight, onto Braeswood, as N. MacGregor bears right
Follow Braeswood to Holcombe Boulevard
Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker

Traveling south from Interstate 45

Exit onto U.S. 59 south
From U.S. 59, exit onto Texas 288 and follow it south to the N. MacGregor exit
Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard
Continue heading straight, onto Braeswood, as N. MacGregor bears right
Follow Braeswood to Holcombe Boulevard
Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker

Traveling north from Hobby Airport / Interstate 45

Take Broadway Street north to Interstate 45
Turn left (north) on I-45 and follow it to Interstate 610
Exit onto I-610 and follow it to the Fannin Street exit
Turn right (north) on Fannin Street and follow it to Holcombe Boulevard
Turn right (east) on Holcombe and follow it to the appropriate Entrance Marker

Traveling west from Interstate 10

Exit U.S. 59, heading south
From U.S. 59, exit onto Texas 288 and follow it south to the N. MacGregor exit
Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard
Continue heading straight, onto Braeswood, as N. MacGregor bears right
Follow Braeswood to Holcombe Boulevard
Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker

Traveling east from Interstate 10

Exit onto Interstate 45 south
From I-45, exit onto U.S. 59 south
From U.S. 59, exit onto Texas 288 heading south and follow it south to the N. MacGregor exit
Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard
Continue heading straight, onto Braeswood, as N. MacGregor bears right
Follow Braeswood to Holcombe Boulevard
Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker

Traveling north from Texas 288

Take the N. MacGregor exit
Turn left (west) onto N. MacGregor and follow it to Braeswood Boulevard
Continue heading straight, onto Braeswood, as N. MacGregor bears right
Follow Braeswood to Holcombe Boulevard
Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker

Traveling south from U.S. 290

Merge onto Interstate 610 south
Take I-610 south exit onto Interstate 10 east
From 1-10 exit onto U.S. 59 south
From U.S. 59, exit onto Texas 288 and follow it south to the N. MacGregor exit
Turn right (west) onto N. MacGregor and follow it to Braeswood Boulevard
Continue heading straight, onto Braeswood, as N. MacGregor bears right
Follow Braeswood to Holcombe Boulevard
Turn right (west) onto Holcombe and follow it to the appropriate Entrance Marker

Numbered entry markers

Numbered entrance markers on the Texas Medical Center and MD Anderson Campus help visitors identify the best entrance to bring a patient or self-park. To support our no visitors policy, valet operations have closed at all of our Texas Medical Center campus buildings. Use the key below to find the best entrance marker for your visit. Review our drop-off and pick-up procedures.

Entrance 2