Videos
In this episode, Editor at Large Ushma Neill interviews Dr. Zhijian (James) Chen. Zhijian (James) Chen (University of Texas Southwestern and HHMI) has had a storied research career focused on the molecular mechanisms of innate immunity, the body's immediate response to pathogens. His discovery of the cGAS enzyme that senses foreign and self-DNA brought him to New York to accept the 2024 Albert Lasker Basic Medical Research Award for a recent conversation.
In this episode, Laura Ondrisova describes how this manuscript examines a non-genetic adaptation to BTK inhibitor therapy in chronic lymphocytic leukemia that involves Akt activation via FoxO1/Rictor axis.
In this episode, Andreas Patsalos and Laszlo Nagy explain that their findings suggest that macrophage subtypes mediated the development of the highly ordered architecture of regenerative tissues, unveiling the principles of the structured yet dynamic nature of regenerative inflammation supporting effective tissue repair.
In this episode, Ushma Neill speaks with the living Editors in Chief of the Journal of Clinical Investigation. They were asked to reflect on their time as editors and their favorite memories.
In this episode, Laszlo Nagy and colleagues, explain that macrophages coordinate tissue repair by promoting regenerative inflammation. They discovered diverse myeloid cell subsets that organize in functional multilayered tissue zones, crucial for effective muscle repair.
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ISSN: 0021-9738 (print), 1558-8238 (online)