The obsoletion of XPO:0100068 (abnormal anatomical region) has left several terms without a path to XPO:00000000 (Xenopus Phenotype). Perhaps rather than being obsoleted this needs to be part of something equivalent to the Gene Ontology's 'gocheck_do_not_manually_annotate' subset of terms which are required structurally in the ontology but are not themselves appropriate for use in annotation.

See below for the orphaned anatomical region branches.