Helena Hogberg, PhD, The National Institute of Environmental Health Sciences, United States of America
Nicole Kleinstreuer, PhD, The National Institute of Environmental Health Sciences, United States of America
Kim To, PhD, Inotiv, United States of America
Image credit: Paul Windsor
Human Genomics invites contributions to this Collection focusing on the development and use of New Approach Methodologies (NAMs) such as in vitro, in silico and small organism models, that address variability or factors associated with susceptibility to adverse effects of chemical exposure. Population-level variability and susceptibility can arise from numerous factors such as genetics, life stage, concurrent stressors, and co-morbidities. Papers are encouraged to deal with human health risk assessment and feature research developing, refining, or implementing NAMs with consideration of population variability or susceptibility.
Comprehensive environmental risk characterization, encompassing physical, chemical, social, ecological, and lifestyle stressors, necessitates innovative approaches to handle the escalating complexity. This is ...
The merging of physiology and toxicokinetics, or pharmacokinetics, with computational modeling to characterize dosimetry has led to major advances for both the chemical and pharmaceutical research arenas. Driv...
4-methylimidazole is a ubiquitous and potentially carcinogenic environmental toxicant. Genetic factors that contribute to variation in susceptibility to its toxic effects are challenging to assess in human pop...
Persistent racial disparities in health outcomes have catalyzed legislative reforms and heightened scientific focus recently. However, despite the well-documented properties of skin pigments in binding drug co...
Per- and poly-fluoroalkyl substances (PFAS) are emerging contaminants of concern because of their wide use, persistence, and potential to be hazardous to both humans and the environment. Several PFAS have been...
Before submitting a manuscript, please read our submission guidelines. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "New Approach Methodologies to Address Population Variability and Susceptibility in Human Risk Assessment" from the dropdown menu.
Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.
The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.