The Traditional Medicine and Modern Medicine from Natural Products

Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new drugs; however, challenges, including the cost and time taken for traditional drug discovery processes and the subsequent lack of investment from the pharmaceutical industry, are associated with these areas. New techniques are producing compounds with appropriate activity at a faster rate. While the formulation of these combined with drug-delivery systems offers a promising approach for expanding the drug developments available to modern medicine. Here, various classes of drug-delivery systems are described and the advantages they bring to small molecule and biotherapeutic targeting are highlighted. This is an attractive approach to the pharmaceutical industry and the rising trend in research in this area is examined in brief. New medicines are constantly being developed or repurposed, aimed at curing or preventing diseases or conditions where therapeutic product availability is lacking, or to reduce side effects, improve quality of life, reduce the burden on the cost of healthcare systems, while significantly extending patients' lives. However, drug discovery, research and development (R&D) can be an extensive process lasting over 7-10 years, with an average cost of $2.6 billion for each successful drug that reaches the market [1]. These substantial cost and time factors originate from the scientific, technical and regulatory challenges that are needed to fully understand the drug mechanisms of action and physiological interactions for complex diseases at molecular level. Achieving viable commercial success subsequently

Statement of Purpose: Although 75% of breast cancer patients may use integrative medicine, only 11.5% earlystage breast cancer patients believe integrative medicine has anticancer activity. The gap in users of and firm believers in integrative medicine indicates a need to increase awareness of integrative medicine's applicability to curative cancer treatment. As diet, nutraceuticals, and traditional Chinese medicine are used by up to 82% of cancer patients who use integrative medicine, this paper focuses on nutraceuticals. As female cancer patients are most likely to use integrative medicine, nutraceuticals specific to breast, cervical, endometrial, and ovarian cancer are reviewed.Methods: PubMed searches in September 2016 and January 2017, and accompanying hand searches were performed for English language, free full text articles published from 2012 onwards. Search terms were combinations of the key words: Homeopathy, phytochemicals, breast cancer, cervical cancer, endometrial cancer, ovarian cancer, cancer, prevention, treatment. Curative nutraceutical treatments were taken from these searches. Supplemental hand searches were performed as needed. Findings:Integrative nutraceutical therapies are based on biologic plausibility. Individual nutraceuticals are frequently comprised of numerous phytochemical types, and have multiple mechanisms of action. Agonistantagonist mechanisms are not exclusive to phytoestrogens, complicating which derivative or whole nutraceutical to use. Research on breast and cervical cancer inhibitors has seemingly outpaced that for endometrial and ovarian cancer. Breast cancer inhibitors include terpenes, isoflavones, organosulphurs, organoselenium compounds, and withanolides. Conclusion and Significance:Potential nutraceutical candidates for curative cancer treatment abound. Discerning which constituents, which extraction method, and which delivery method to use for an efficacious treatment is an essential, lengthy process. If nutraceuticals such as limonene and Kahalalide F move forward to Phase III trials a nutraceutical cancer treatment pipeline may be established. Withaferin-A and derivatives for breast and ovarian cancer appear to be the leading gynecologic cancer nutraceutical drug candidates.

Objective: Indian Traditional Medicine, the foundation of age-old practice of medicine in the world, has played an essential role in human health care service and welfare from its inception. Likewise, all traditional medicines are of its own regional effects and dominant in the West Asian nations; India, Pakistan, Tibet, and so forth, East Asian nations; China, Korea, Japan, Vietnam, and so forth, Africa, South and Central America. This article is an attempt to illuminate Indian traditional medical service and its importance, based on recent methodical reviews.Methods: Web search engines for example; Google, Science Direct and Google Scholar were employed for reviews as well as for meta-analysis. Results:There is a long running debate between individuals, who utilize Indian Traditional Medicines for different ailments and disorders, and the individuals who depend on the present day; modern medicine for cure. The civil argument between modern medicine and traditional medicines comes down to a basic truth; each person, regardless of education or sickness, ought to be educated about the actualities concerning their illness and the associated side effects of medicines. Therapeutic knowledge of Indian traditional medicine has propelled various traditional approaches with similar or different theories and methodologies, which are of regional significance. Conclusion:To extend research exercises on Indian Traditional Medicine, in near future, and to explore the phytochemicals; the current review will help the investigators involved in traditional medicinal pursuit.