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. 1998 Mar;6(1):39-41.
doi: 10.1076/ocii.6.1.39.8084.

HLA typing in patients with multiple evanescent white dot syndrome (MEWDS)

F X Borruat  1 , C P Herbort, F Spertini, A B Desarnaulds
Affiliations

HLA typing in patients with multiple evanescent white dot syndrome (MEWDS)

F X Borruat et al. Ocul Immunol Inflamm. 1998 Mar.

Abstract

Background: Multiple evanescent white dot syndrome (MEWDS) is an acquired chorioretinal disorder of unknown etiology. We investigated the possibility that MEWDS might be related to a specific HLA subtyping.

Methods/results: Blood was obtained from nine patients affected by MEWDS. HLA-B51 was found in four of these nine patients with MEWDS.

Conclusion: There was a 3.7-fold increased frequency of HLA-B51 in patients affected by MEWDS (relative risk 5.86). MEWDS might then be related to the presence of a specific HLA subtype, HLA-B51. However, due to the small sample size, our results need to be confirmed by further testing.

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