Small-intestinal submucosa for bladder augmentation: a review of preclinical studies
- PMID: 9775425
- DOI: 10.1007/s003450050064
Small-intestinal submucosa for bladder augmentation: a review of preclinical studies
Abstract
The need to find an alternative to the use of bowel for urinary reconstruction has renewed research interests involving bladder regeneration. Historically, alloplastic and biodegradable materials have demonstrated bladder regeneration; however, high complication rates and unreliable regenerative results have prevented any of these materials from being used clinically. Small-intestinal submucosa (SIS) is an acellular, nonimmunogenic, biodegradable, xenogeneic, collagen-based material that is derived from the submucosa layer of porcine small intestine. SIS has demonstrated regenerative capacities in multiple organ systems, including the aorta, vena cava, ligaments, tendons, abdominal wall, and skin. SIS has also demonstrated long-term reliable regenerative results in the rat and canine bladder-augmentation models. This article reviews the preclinical studies involving the use of SIS for bladder augmentation.
Similar articles
-
Understanding roles of porcine small intestinal submucosa in urinary bladder regeneration: identification of variable regenerative characteristics of small intestinal submucosa.Tissue Eng Part B Rev. 2014 Feb;20(1):73-83. doi: 10.1089/ten.TEB.2013.0126. Epub 2013 Jul 25. Tissue Eng Part B Rev. 2014. PMID: 23777420 Free PMC article. Review.
-
Regional variations in small intestinal submucosa evoke differences in inflammation with subsequent impact on tissue regeneration in the rat bladder augmentation model.BJU Int. 2010 May;105(10):1462-8. doi: 10.1111/j.1464-410X.2009.08965.x. Epub 2009 Oct 26. BJU Int. 2010. PMID: 19863527
-
Regenerative urinary bladder augmentation using small intestinal submucosa: urodynamic and histopathologic assessment in long-term canine bladder augmentations.J Urol. 1996 Jun;155(6):2098-104. doi: 10.1016/s0022-5347(01)66117-2. J Urol. 1996. PMID: 8618344
-
Use of porcine small intestinal submucosa in bladder augmentation in rabbit: long-term histological outcome.ANZ J Surg. 2008 Jan-Feb;78(1-2):82-6. doi: 10.1111/j.1445-2197.2007.04361.x. ANZ J Surg. 2008. PMID: 18199213
-
Urologic tissue engineering with small-intestinal submucosa: potential clinical applications.World J Urol. 2000 Feb;18(1):26-30. doi: 10.1007/PL00007071. World J Urol. 2000. PMID: 10766040 Review.
Cited by
-
The application of small intestinal submucosa in tissue regeneration.Mater Today Bio. 2024 Mar 18;26:101032. doi: 10.1016/j.mtbio.2024.101032. eCollection 2024 Jun. Mater Today Bio. 2024. PMID: 38533376 Free PMC article. Review.
-
Remodelling landscape of tissue-engineered bladder with porcine small intestine submucosa using single-cell RNA sequencing.Cell Prolif. 2023 Jan;56(1):e13343. doi: 10.1111/cpr.13343. Epub 2022 Sep 30. Cell Prolif. 2023. PMID: 36177893 Free PMC article.
-
Tissue Engineering and Regenerative Medicine in Pediatric Urology: Urethral and Urinary Bladder Reconstruction.Int J Mol Sci. 2022 Jun 7;23(12):6360. doi: 10.3390/ijms23126360. Int J Mol Sci. 2022. PMID: 35742803 Free PMC article. Review.
-
Porcine Small Intestinal Submucosa (SIS) as a Suitable Scaffold for the Creation of a Tissue-Engineered Urinary Conduit: Decellularization, Biomechanical and Biocompatibility Characterization Using New Approaches.Int J Mol Sci. 2022 Mar 4;23(5):2826. doi: 10.3390/ijms23052826. Int J Mol Sci. 2022. PMID: 35269969 Free PMC article.
-
Surface modification of small intestine submucosa in tissue engineering.Regen Biomater. 2020 Aug;7(4):339-348. doi: 10.1093/rb/rbaa014. Epub 2020 May 18. Regen Biomater. 2020. PMID: 32793379 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources