Semiconductor nanocrystals as fluorescent biological labels
- PMID: 9748157
- DOI: 10.1126/science.281.5385.2013
Semiconductor nanocrystals as fluorescent biological labels
Abstract
Semiconductor nanocrystals were prepared for use as fluorescent probes in biological staining and diagnostics. Compared with conventional fluorophores, the nanocrystals have a narrow, tunable, symmetric emission spectrum and are photochemically stable. The advantages of the broad, continuous excitation spectrum were demonstrated in a dual-emission, single-excitation labeling experiment on mouse fibroblasts. These nanocrystal probes are thus complementary and in some cases may be superior to existing fluorophores.
Comment in
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Semiconductor beacons light up cell structures.Science. 1998 Sep 25;281(5385):1930-1. doi: 10.1126/science.281.5385.1930b. Science. 1998. PMID: 9767032 No abstract available.
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