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Review
. 1998 Sep 21;142(6):1395-8.
doi: 10.1083/jcb.142.6.1395.

The heterogeneity of ER Ca2+ stores has a key role in nonmuscle cell signaling and function

J Meldolesi  1 , T Pozzan
Affiliations
Review

The heterogeneity of ER Ca2+ stores has a key role in nonmuscle cell signaling and function

J Meldolesi et al. J Cell Biol. .
No abstract available

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Figures

Figure 1
Figure 1
Distribution of total calcium in a PC12 pheochromocytoma cell, as revealed by electron energy loss imaging analysis. The calcium signal, expressed in false colors, is superimposed on a conventional image from a thin section of a quick frozen–freeze dried cell, including a mitochondrion and a few parallel running ER cisternae. Notice the calcium-rich ER cisternae in continuity with other cisternae where the signal remains below threshold, as it is the case with the mitochondrion and the plasmalemma. Reproduced with permission from Pezzati et al. (31).
See this image and copyright information in PMC

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References

    1. Bennett DL, Cheek TR, Berridge MJ, De Smedt H, Parys JB, Missiaen L, Bootman MD. Expression and function of ryanodine receptors in nonexcitable cells. J Biol Chem. 1996;271:6356–6362. - PubMed
    1. Bootman MD, Berridge MJ, Lipp P. Cooking with calcium: the recipes for composing global signals from elementary events. Cell. 1997;91:367–373. - PubMed
    1. Chavis P, Fagni L, Lansman JB, Bockaert J. Functional coupling between ryanodine receptors and L-type calcium channels in neurons. Nature. 1996;382:719–722. - PubMed
    1. Dolmetsch RE, Xu K, Lewis RS. Calcium oscillations increase the efficiency and specificity of gene expression. Nature. 1998;392:933–936. - PubMed
    1. Fields RD, Eshete F, Stevens B, Itoh K. Action potential-dependent regulation of gene expression: temporal specificity in Ca2+, cAMP-responsive element binding proteins, and mitogen-activated protein kinase signaling. J Neurosci. 1997;17:7252–7266. - PMC - PubMed