Review
doi: 10.1046/j.1365-2443.1998.00191.x.
How protein reads the stop codon and terminates translation
Affiliations
- PMID: 9685178
- DOI: 10.1046/j.1365-2443.1998.00191.x
Item in Clipboard
Review
How protein reads the stop codon and terminates translation
Genes Cells.
1998 May.
Free article
Abstract
Translation termination requires two codon-specific protein-release factors in prokaryotes and one factor in eukaryotes. The underlying mechanism for stop codon recognition, as well as the biological meaning of the conservation of one or two release factors in the evolutionary kingdoms, are not known. The recent discovery of release factor genes and the molecular mimicry between translational factors and tRNA provide us with clues to the mechanisms of how proteins read the stop codon and terminate translation, shedding some light on the evolutionary aspect of release factors.
Similar articles
-
Terminating eukaryote translation: domain 1 of release factor eRF1 functions in stop codon recognition.RNA. 2000 Sep;6(9):1236-47. doi: 10.1017/s1355838200000777. RNA. 2000. PMID: 10999601 Free PMC article.
-
Convergence and constraint in eukaryotic release factor 1 (eRF1) domain 1: the evolution of stop codon specificity.Nucleic Acids Res. 2002 Jan 15;30(2):532-44. doi: 10.1093/nar/30.2.532. Nucleic Acids Res. 2002. PMID: 11788716 Free PMC article.
-
Kinetics of stop codon recognition by release factor 1.Biochemistry. 2009 Dec 1;48(47):11178-84. doi: 10.1021/bi901577d. Biochemistry. 2009. PMID: 19874047 Free PMC article.
-
[Non-canonical decoding events at stop codons in eukaryotes].Mol Biol (Mosk). 2006 Jul-Aug;40(4):731-41. Mol Biol (Mosk). 2006. PMID: 16913232 Review. Russian.
-
[Molecular mechanism of stop codon recognition by eRF1: a wobble hypothesis for peptide anticodons].Tanpakushitsu Kakusan Koso. 2001 Dec;46(15):2163-70. Tanpakushitsu Kakusan Koso. 2001. PMID: 11762076 Review. Japanese. No abstract available.
Cited by
-
Multiple conversion between the genes encoding bacterial class-I release factors.Sci Rep. 2015 Aug 10;5:12406. doi: 10.1038/srep12406. Sci Rep. 2015. PMID: 26257102 Free PMC article.
-
The ribosomal binding and peptidyl-tRNA hydrolysis functions of Escherichia coli release factor 2 are linked through residue 246.RNA. 2000 Dec;6(12):1704-13. doi: 10.1017/s135583820000131x. RNA. 2000. PMID: 11142371 Free PMC article.
-
C-terminal interaction of translational release factors eRF1 and eRF3 of fission yeast: G-domain uncoupled binding and the role of conserved amino acids.RNA. 1999 Jun;5(6):739-50. doi: 10.1017/s135583829998216x. RNA. 1999. PMID: 10376874 Free PMC article.
-
A peptide chain release factor 2 affects the stability of UGA-containing transcripts in Arabidopsis chloroplasts.Plant Cell. 2002 Dec;14(12):3255-69. doi: 10.1105/tpc.006809. Plant Cell. 2002. PMID: 12468741 Free PMC article.
-
Are stop codons recognized by base triplets in the large ribosomal RNA subunit?RNA. 2005 Oct;11(10):1478-84. doi: 10.1261/rna.2780505. RNA. 2005. PMID: 16199759 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
