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Review
. 1998:19:17-34.
doi: 10.1146/annurev.publhealth.19.1.17.

Econometrics in outcomes research: the use of instrumental variables

Affiliations
Review

Econometrics in outcomes research: the use of instrumental variables

J P Newhouse et al. Annu Rev Public Health. 1998.

Abstract

We describe an econometric technique, instrumental variables, that can be useful in estimating the effectiveness of clinical treatments in situations when a controlled trial has not or cannot be done. This technique relies upon the existence of one or more variables that induce substantial variation in the treatment variable but have no direct effect on the outcome variable of interest. We illustrate the use of the technique with an application to aggressive treatment of acute myocardial infarction in the elderly.

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