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Comparative Study
. 1998 Apr 30;17(8):873-90.
doi: 10.1002/(sici)1097-0258(19980430)17:8<873::aid-sim779>3.0.co;2-i.

Interval estimation for the difference between independent proportions: comparison of eleven methods

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Comparative Study

Interval estimation for the difference between independent proportions: comparison of eleven methods

R G Newcombe. Stat Med. .

Erratum in

  • Stat Med 1999 May 30;18(10):1293

Abstract

Several existing unconditional methods for setting confidence intervals for the difference between binomial proportions are evaluated. Computationally simpler methods are prone to a variety of aberrations and poor coverage properties. The closely interrelated methods of Mee and Miettinen and Nurminen perform well but require a computer program. Two new approaches which also avoid aberrations are developed and evaluated. A tail area profile likelihood based method produces the best coverage properties, but is difficult to calculate for large denominators. A method combining Wilson score intervals for the two proportions to be compared also performs well, and is readily implemented irrespective of sample size.

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