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Case Reports
. 1997 Dec;17(6):403-5.

[An exceptional variety of medulloblastoma: melanotic medulloblastoma]

[Article in French]
F Baylac  1 , A Martinoli, B Marie, S Bracard, J C Marchal, P Bey, D Sommelet, J Hassoun, F Plénat
Affiliations
  • PMID: 9526628
Case Reports

[An exceptional variety of medulloblastoma: melanotic medulloblastoma]

[Article in French]
F Baylac et al. Ann Pathol. 1997 Dec.

Abstract

We report a new case of melanotic medulloblastoma of the vermis in a 3 1/2 year old boy. This tumor showed a typical histological appearance with pseudoepithelial pigmented structures immunoreactive for S100 protein and vimentin. The tumor did not recur after total surgical removal and post operative radiation. However, after a 10 year follow-up, imaging demonstrated that a second tumor occurred in the left cerebellar hemisphere, which, on histological examination, was a typical glioblastoma. Hypothesis concerning the histogenesis of the second tumor, as well as a causal association with radiation therapy and possible contribution of growth hormone therapy are discussed.

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