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Comparative Study
. 1998 Jan 15;26(2):655-61.
doi: 10.1093/nar/26.2.655.

Three-dimensional structure of the yeast ribosome

A Verschoor  1 , J R Warner, S Srivastava, R A Grassucci, J Frank
Affiliations
Comparative Study

Three-dimensional structure of the yeast ribosome

A Verschoor et al. Nucleic Acids Res. .

Abstract

The 80S ribosome from Saccharomyces cerevisiae has been reconstructed from cryo electron micrographs to a resolution of 35 A. It is strikingly similar to the 70S ribosome from Escherichia coli, while displaying the characteristic eukaryotic features familiar from reconstructions of ribosomes from higher eukaryotes. Aside from the elaboration of a number of peripherally located features on the two subunits and greater overall size, the largest difference between the yeast and E.coli ribosomes is in a mass increase on one side of the large (60S) subunit. It thus appears more elliptical than the characteristically globular 50S subunit from E.coli. The interior of the 60S subunit reveals a variable diameter tunnel spanning the subunit between the interface canyon and a site on the lower back of the subunit, presumably the exit site through which the nascent polypeptide chain emerges from the ribosome.

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References

    1. Structure. 1995 Aug 15;3(8):815-21 - PubMed
    1. Nature. 1995 Aug 3;376(6539):441-4 - PubMed
    1. J Cell Biol. 1996 May;133(3):495-505 - PubMed
    1. Biochem Cell Biol. 1995 Nov-Dec;73(11-12):757-65 - PubMed
    1. Genes Dev. 1997 Sep 15;11(18):2396-413 - PubMed

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