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. 1997 May 23;757(2):285-90.
doi: 10.1016/s0006-8993(97)00337-5.

Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates

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Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates

E D Herzog et al. Brain Res. .

Abstract

The suprachiasmatic nucleus (SCN) of the mammalian hypothalamus functions as a circadian pacemaker. This study used multimicroelectrode plates to measure extracellular action potential activity simultaneously from multiple sites within the cultured mouse SCN. Neurons within the isolated mouse SCN expressed a circadian rhythm in spontaneous firing rate for weeks in culture.

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