Comparative Study
doi: 10.1271/bbb.61.905.
Zinc finger-like motif conserved in a family of RNA binding proteins
Affiliations
- PMID: 9178570
- DOI: 10.1271/bbb.61.905
Item in Clipboard
Comparative Study
Zinc finger-like motif conserved in a family of RNA binding proteins
Biosci Biotechnol Biochem.
1997 May.
Free article
Abstract
NP220s compose a family of RNA binding proteins together with matrin 3, one of major proteins of the nuclear matrix. They have repeats of RNA recognition motif (RRM; MH2) homologous to RRM in heterogeneous nuclear RNPs I/L in addition to MH1 and MH3 with unknown function. In search of additional homologous sequences, we found the reported sequence of rat matrin 3 is partially incorrect. Correction of this sequence showed that the NP220 family has a fourth homologous motif with the characteristics of a Cys2-His2 zinc finger-like motif. The sequence of this motif is perfectly conserved in human and mouse NP220s despite their 75% overall sequence homology.
Similar articles
-
A family of novel DNA-binding nuclear proteins having polypyrimidine tract-binding motif and arginine/serine-rich motif.Biochem Biophys Res Commun. 1996 Jun 14;223(2):427-33. doi: 10.1006/bbrc.1996.0910. Biochem Biophys Res Commun. 1996. PMID: 8670298
-
A large DNA-binding nuclear protein with RNA recognition motif and serine/arginine-rich domain.J Biol Chem. 1996 May 24;271(21):12525-31. doi: 10.1074/jbc.271.21.12525. J Biol Chem. 1996. PMID: 8647861
-
Identification of zinc finger mRNAs using domain-specific differential display.Anal Biochem. 1996 May 1;236(2):348-52. doi: 10.1006/abio.1996.0178. Anal Biochem. 1996. PMID: 8660516
-
The SCAN domain family of zinc finger transcription factors.Gene. 2005 Oct 10;359:1-17. doi: 10.1016/j.gene.2005.06.022. Gene. 2005. PMID: 16139965 Review.
-
Sequence-specific DNA recognition by Cys2, His2 zinc fingers.Ann N Y Acad Sci. 1994 Jul 29;726:92-102; discussion 102-4. doi: 10.1111/j.1749-6632.1994.tb52800.x. Ann N Y Acad Sci. 1994. PMID: 8092710 Review. No abstract available.
Cited by
-
The cohesin complex: sequence homologies, interaction networks and shared motifs.Genome Biol. 2001;2(3):RESEARCH0009. doi: 10.1186/gb-2001-2-3-research0009. Epub 2001 Mar 6. Genome Biol. 2001. PMID: 11276426 Free PMC article.
-
Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106.Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4494-503. doi: 10.1073/pnas.1608423113. Epub 2016 Jul 14. Proc Natl Acad Sci U S A. 2016. PMID: 27418600 Free PMC article.
-
Domain function and predicted structure of three heterodimeric endonuclease subunits of RNA editing catalytic complexes in Trypanosoma brucei.Nucleic Acids Res. 2022 Sep 23;50(17):10123-10139. doi: 10.1093/nar/gkac753. Nucleic Acids Res. 2022. PMID: 36095119 Free PMC article.
-
Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNA.Mol Cell Biol. 2000 Jul;20(13):4910-21. doi: 10.1128/MCB.20.13.4910-4921.2000. Mol Cell Biol. 2000. PMID: 10848616 Free PMC article.
-
Luc7p, a novel yeast U1 snRNP protein with a role in 5' splice site recognition.Genes Dev. 1999 Sep 15;13(18):2425-38. doi: 10.1101/gad.13.18.2425. Genes Dev. 1999. PMID: 10500099 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous
