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Review
. 1997 Apr;9(2):148-54.
doi: 10.1016/s0955-0674(97)80056-7.

Reversible palmitoylation of signaling proteins

Affiliations
Review

Reversible palmitoylation of signaling proteins

S M Mumby. Curr Opin Cell Biol. 1997 Apr.

Abstract

Palmitoylation is unique among lipid modifications of proteins in that it is reversible and regulable. Recent advances in the study of palmitoylation include the following: the correlation of this modification with the localization of a signaling protein to specific membrane subdomains; the demonstration of a specific protein-protein interaction that is promoted by palmitoylation; and the identification, characterization, and purification of enzymes catalyzing this modification.

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