Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations
- PMID: 8978055
- PMCID: PMC1207719
- DOI: 10.1093/genetics/144.4.1681
Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations
Abstract
Screens for zygotic lethal mutations that are associated with specific maternal effect lethal phenotypes have only been conducted for the X chromosome. To identify loci on the autosomes, which represent four-fifths of the Drosophila genome, we have used the autosomal "FLP-DFS" technique to screen a collection of 496 P element-induced mutations established by the Berkeley Drosophila Genome Project. We have identified 64 new loci whose gene products are required for proper egg formation or normal embryonic development.
Similar articles
-
Screening of larval/pupal P-element induced lethals on the second chromosome in Drosophila melanogaster: clonal analysis and morphology of imaginal discs.Mol Gen Genet. 1998 Jan;257(2):103-12. doi: 10.1007/pl00008620. Mol Gen Genet. 1998. PMID: 9491068
-
Zygotic lethals with specific maternal effect phenotypes in Drosophila melanogaster. I. Loci on the X chromosome.Genetics. 1989 Feb;121(2):333-52. doi: 10.1093/genetics/121.2.333. Genetics. 1989. PMID: 2499512 Free PMC article.
-
The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster.Genetics. 1996 Dec;144(4):1673-9. doi: 10.1093/genetics/144.4.1673. Genetics. 1996. PMID: 8978054 Free PMC article.
-
Transposable elements and fitness in Drosophila melanogaster.Genome. 1989;31(1):284-95. doi: 10.1139/g89-046. Genome. 1989. PMID: 2556325 Review.
-
Gene disruptions using P transposable elements: an integral component of the Drosophila genome project.Proc Natl Acad Sci U S A. 1995 Nov 21;92(24):10824-30. doi: 10.1073/pnas.92.24.10824. Proc Natl Acad Sci U S A. 1995. PMID: 7479892 Free PMC article. Review.
Cited by
-
Australian black field crickets show changes in neural gene expression associated with socially-induced morphological, life-history, and behavioral plasticity.BMC Genomics. 2016 Oct 24;17(1):827. doi: 10.1186/s12864-016-3119-y. BMC Genomics. 2016. PMID: 27776492 Free PMC article.
-
Molecular foundations of reproductive lethality in Arabidopsis thaliana.PLoS One. 2011;6(12):e28398. doi: 10.1371/journal.pone.0028398. Epub 2011 Dec 2. PLoS One. 2011. PMID: 22164284 Free PMC article.
-
The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling.EMBO J. 2005 Oct 5;24(19):3493-503. doi: 10.1038/sj.emboj.7600817. Epub 2005 Sep 15. EMBO J. 2005. PMID: 16163385 Free PMC article.
-
dCtBP-dependent and -independent repression activities of the Drosophila Knirps protein.Mol Cell Biol. 2000 Oct;20(19):7247-58. doi: 10.1128/MCB.20.19.7247-7258.2000. Mol Cell Biol. 2000. PMID: 10982842 Free PMC article.
-
Hedgehog and Wingless stabilize but do not induce cell fate during Drosophila dorsal embryonic epidermal patterning.Development. 2008 Aug;135(16):2767-75. doi: 10.1242/dev.017814. Epub 2008 Jul 9. Development. 2008. PMID: 18614578 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases