Review
doi: 10.1093/clinids/21.supplement_2.s162.
NO inhibitions: antimicrobial properties of nitric oxide
Affiliations
- PMID: 8845445
- DOI: 10.1093/clinids/21.supplement_2.s162
Item in Clipboard
Review
NO inhibitions: antimicrobial properties of nitric oxide
Clin Infect Dis.
1995 Oct.
Abstract
The past decade has witnessed a veritable explosion of interest in the simple molecule nitric oxide (NO) as a vasodilator, neurotransmitter, and antimicrobial agent. NO and other reactive nitrogen intermediates exhibit cytostatic or cytocidal activity against a remarkable breadth of pathogenic microorganisms. Mammalian cells, including human cells, produce nitric oxide both constitutively and inducibly in response to inflammatory stimuli. This review will provide a brief overview of current knowledge regarding the antimicrobial activity of NO and the possible importance of this activity in infection, particularly with regard to intracellular pathogens.
Similar articles
-
Lung surfactant and reactive oxygen-nitrogen species: antimicrobial activity and host-pathogen interactions.Am J Physiol Lung Cell Mol Physiol. 2001 Sep;281(3):L517-23. doi: 10.1152/ajplung.2001.281.3.L517. Am J Physiol Lung Cell Mol Physiol. 2001. PMID: 11504674 Review.
-
Nitric oxide-induced nitrative stress involved in microbial pathogenesis.J Pharmacol Sci. 2005 Jun;98(2):117-29. doi: 10.1254/jphs.crj05004x. Epub 2005 Jun 4. J Pharmacol Sci. 2005. PMID: 15937405 Review.
-
[The antimicrobial activity of nitric oxide and its role in the infectious process].Zh Mikrobiol Epidemiol Immunobiol. 1999 Sep-Oct;(5):61-7. Zh Mikrobiol Epidemiol Immunobiol. 1999. PMID: 10852025 Review. Russian.
-
NADPH oxidase, Nramp1 and nitric oxide synthase 2 in the host antimicrobial response.Rev Immunogenet. 2000;2(3):387-415. Rev Immunogenet. 2000. PMID: 11256747 Review.
-
Antimicrobial properties of nitric oxide and its application in antimicrobial formulations and medical devices.Appl Microbiol Biotechnol. 2010 Sep;88(2):401-7. doi: 10.1007/s00253-010-2733-x. Epub 2010 Aug 3. Appl Microbiol Biotechnol. 2010. PMID: 20680266 Review.
Cited by
-
Nitric oxide and infectious diseases.Arch Dis Child. 1999 Aug;81(2):185-8. doi: 10.1136/adc.81.2.185. Arch Dis Child. 1999. PMID: 10490536 Free PMC article. Review. No abstract available.
-
In vitro and in vivo assessment of Salmonella enterica serovar Typhimurium DT104 virulence.Infect Immun. 2001 Jul;69(7):4673-7. doi: 10.1128/IAI.69.7.4673-4677.2001. Infect Immun. 2001. PMID: 11402014 Free PMC article.
-
Advances in Nitric Oxide-Releasing Hydrogels for Biomedical Applications.Curr Opin Colloid Interface Sci. 2023 Aug;66:101704. doi: 10.1016/j.cocis.2023.101704. Epub 2023 May 15. Curr Opin Colloid Interface Sci. 2023. PMID: 37694274 Free PMC article.
-
Analysis of virulence of clinical isolates of Salmonella enteritidis in vivo and in vitro.Infect Immun. 1999 Nov;67(11):5651-7. doi: 10.1128/IAI.67.11.5651-5657.1999. Infect Immun. 1999. PMID: 10531212 Free PMC article.
-
In vitro evaluation of a new treatment for urinary tract infections caused by nitrate-reducing bacteria.Antimicrob Agents Chemother. 2003 Dec;47(12):3713-8. doi: 10.1128/AAC.47.12.3713-3718.2003. Antimicrob Agents Chemother. 2003. PMID: 14638471 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous
