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. 1978 Apr 15;1(8068):795-7.
doi: 10.1016/s0140-6736(78)92998-7.

Circadian variation of blood-pressure

Circadian variation of blood-pressure

M W Millar-Craig et al. Lancet. .

Abstract

Continuous intra-arterial blood-pressure and electrocardiogram recordings were obtained in twenty hypertensive and five normotensive ambulant patients. Blood-pressure was highest mid-morning and then fell progressively throughout the remainder of the day. Blood-pressure was lowest at 3 A.M. and began to rise again during the early hours of the morning before waking. These findings may have important consequences with regard to the therapeutic management of hypertension.

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