Integrin transmembrane signaling and cytoskeletal control
- PMID: 8573343
- DOI: 10.1016/0955-0674(95)80110-3
Integrin transmembrane signaling and cytoskeletal control
Abstract
Integrins are remarkably multifunctional: they mediate cell adhesion and migration, orchestrate organization of the actin-based cytoskeleton, and activate signal transduction pathways. Recent studies have identified a variety of steps and hierarchies in these intracellular cytoskeletal and signaling responses, laying the groundwork for future studies on specificity and coordination with responses to growth factors.
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