Respiratory virus infections during anticancer treatment in children
- PMID: 8532427
- DOI: 10.1097/00006454-199508000-00008
Respiratory virus infections during anticancer treatment in children
Abstract
To evaluate the occurrence and clinical significance of respiratory virus infections in children during anticancer treatment, we studied 75 consecutive episodes of febrile infection in 32 children during 17 months. Viral antigen detection for 7 respiratory viruses, viral culture for rhinoviruses and enzyme immunoassay serology were used. Evidence for respiratory virus infection was found in 28 (37%) cases. Rhinovirus was the most common virus detected in 13 (17%) episodes. The other etiologic agents were respiratory syncytial virus (6 episodes), parainfluenza virus type 3 (5 episodes), adenovirus (4 episodes), influenza A virus (3 episodes), and influenza B virus (1 episode). Respiratory virus infections were diagnosed as often in leukopenic as in non-leukopenic patients (37% vs. 38%). In 4 cases bacteremic infection was diagnosed. We found no difference in serum C-reactive protein values when episodes positive for respiratory viruses were compared with virus-negative episodes. Our observations show that respiratory virus infections are common in febrile children receiving anticancer treatment. Diagnostic tests for respiratory viruses should be used more often in evaluation of fever in these patients.
Similar articles
-
Respiratory viral infections in children with leukemia.Pediatr Infect Dis J. 2008 Nov;27(11):974-80. doi: 10.1097/INF.0b013e31817b0799. Pediatr Infect Dis J. 2008. PMID: 18833026
-
Community respiratory viruses as a cause of lower respiratory tract infections following suppressive chemotherapy in cancer patients.J Egypt Natl Canc Inst. 2005 Jun;17(2):121-6. J Egypt Natl Canc Inst. 2005. PMID: 16508683
-
Frequent Respiratory Viral Infections in Children with Febrile Neutropenia - A Prospective Follow-Up Study.PLoS One. 2016 Jun 16;11(6):e0157398. doi: 10.1371/journal.pone.0157398. eCollection 2016. PLoS One. 2016. PMID: 27309354 Free PMC article.
-
Common community respiratory viruses in patients with cancer: more than just "common colds".Cancer. 2003 May 15;97(10):2576-87. doi: 10.1002/cncr.11353. Cancer. 2003. PMID: 12733157 Review.
-
[Asthma and infection: risk or prevention?].Schweiz Med Wochenschr. 1998 Nov 21;128(47):1833-9. Schweiz Med Wochenschr. 1998. PMID: 9864789 Review. German.
Cited by
-
Community-acquired respiratory infections are common in patients with non-Hodgkin lymphoma and multiple myeloma.Support Care Cancer. 2018 Jul;26(7):2425-2431. doi: 10.1007/s00520-018-4079-3. Epub 2018 Feb 9. Support Care Cancer. 2018. PMID: 29427192
-
Viral findings during febrile episodes after cytotoxic chemotherapy in patients with hematological malignancies.Eur J Clin Microbiol Infect Dis. 1998 Aug;17(8):593-4. doi: 10.1007/BF01708628. Eur J Clin Microbiol Infect Dis. 1998. PMID: 9796663 No abstract available.
-
[Children with cancer and respiratory viral infection: epidemiology, diagnosis and treatment options].Enferm Infecc Microbiol Clin. 2011 Jan;29(1):40-51. doi: 10.1016/j.eimc.2010.04.011. Epub 2010 Dec 22. Enferm Infecc Microbiol Clin. 2011. PMID: 21183254 Free PMC article. Review. Spanish.
-
Influenza-associated morbidity in children with cancer.Pediatr Blood Cancer. 2008 May;50(5):983-7. doi: 10.1002/pbc.21472. Pediatr Blood Cancer. 2008. PMID: 18240170 Free PMC article. Clinical Trial.
-
Parainfluenza virus infections in children with hematologic malignancies.Pediatr Infect Dis J. 2011 Oct;30(10):855-9. doi: 10.1097/INF.0b013e31821d190f. Pediatr Infect Dis J. 2011. PMID: 21540759 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials