doi: 10.1038/362722a0.
Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein
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- PMID: 8469283
- DOI: 10.1038/362722a0
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Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein
Nature.
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Abstract
Expression of globin genes in developing erythroid cells is controlled by upstream locus control regions. Activity of these regions in vivo requires an erythroid-specific nuclear factor (NF-E2) that binds AP-1-like recognition sites. Its tissue-specific component (p45 NF-E2) has been characterized by complementary DNA cloning as a new basic region-leucine zipper protein which dimerizes with a ubiquitous partner to form native NF-E2.
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