Familial cold urticaria
- PMID: 8403471
- DOI: 10.1111/j.1365-2230.1993.tb02212.x
Familial cold urticaria
Abstract
Familial cold urticaria (FCU) is a rare autosomal dominant condition, first described in 1940. The onset is in early life in all reported cases. Symptoms are triggered by generalized exposure to cold air, particularly in damp and windy weather. The cutaneous lesions consist of erythematous macules or plaques, urticarial lesions and sometimes petechiae. Associated fever, chills, joint pains, nausea, stiffness and swelling of the hands and feet frequently occur. The symptoms are variable, ranging from mild to incapacitating. The pathogenesis of FCU remains unknown. To our knowledge only 10 pedigrees have been published, seven from the USA and one each from Holland, France and South Africa. We wish to report another extensive pedigree after having had the opportunity to investigate one member of the family in detail. A short form of this pedigree has been published elsewhere.
Similar articles
-
Familial cold urticaria. Investigation of a family and response to stanozolol.Arch Dermatol. 1993 Mar;129(3):343-6. doi: 10.1001/archderm.129.3.343. Arch Dermatol. 1993. PMID: 8447672
-
Familial cold urticaria: a father and daughter with typical clinical and laboratory features.Ann Allergy Asthma Immunol. 1995 Apr;74(4):295-8. Ann Allergy Asthma Immunol. 1995. PMID: 7719887
-
Familial atypical cold urticaria: description of a new hereditary disease.J Allergy Clin Immunol. 2009 Dec;124(6):1245-50. doi: 10.1016/j.jaci.2009.09.035. J Allergy Clin Immunol. 2009. PMID: 19910034 Free PMC article.
-
The spectrum of acquired and familial cold-induced urticaria/urticaria-like syndromes.Immunol Allergy Clin North Am. 2004 May;24(2):259-86, vii. doi: 10.1016/j.iac.2004.01.001. Immunol Allergy Clin North Am. 2004. PMID: 15120151 Review.
-
[Cold-induced urticaria].Allerg Immunol (Paris). 2002 Sep;34(7):255-8. Allerg Immunol (Paris). 2002. PMID: 12389450 Review. French.
Cited by
-
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome.Nat Genet. 2001 Nov;29(3):301-5. doi: 10.1038/ng756. Nat Genet. 2001. PMID: 11687797 Free PMC article.
-
Urticaria. Recognition, causes and treatment.Drugs. 1994 Nov;48(5):717-30. doi: 10.2165/00003495-199448050-00006. Drugs. 1994. PMID: 7530629 Review.
-
Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes.Am J Hum Genet. 2002 Jul;71(1):198-203. doi: 10.1086/341357. Epub 2002 May 24. Am J Hum Genet. 2002. PMID: 12032915 Free PMC article.
-
Identification of a locus on chromosome 1q44 for familial cold urticaria.Am J Hum Genet. 2000 May;66(5):1693-8. doi: 10.1086/302874. Epub 2000 Mar 30. Am J Hum Genet. 2000. PMID: 10741953 Free PMC article.
-
NLRP3 inflammasome and NLRP3-related autoinflammatory diseases: From cryopyrin function to targeted therapies.Front Immunol. 2022 Oct 6;13:1007705. doi: 10.3389/fimmu.2022.1007705. eCollection 2022. Front Immunol. 2022. PMID: 36275641 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical