Review
doi: 10.1016/0955-0674(94)90135-x.
Expanding horizons for receptors coupled to G proteins: diversity and disease
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- PMID: 8024809
- DOI: 10.1016/0955-0674(94)90135-x
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Review
Expanding horizons for receptors coupled to G proteins: diversity and disease
Curr Opin Cell Biol.
1994 Apr.
Abstract
The known repertoire of seven transmembrane domain receptors coupled to G proteins has expanded in several interesting directions. Both loss-of-function and activating mutations have been found at the root of a variety of diseases. More will undoubtedly be uncovered. The diversity of ligands which trigger G protein coupled receptors continues to grow, and with it the variety of known strategies for ligand detection. These and other developments promise continued excitement in this field.
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