Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1995 Feb;63(2):696-9.
doi: 10.1128/iai.63.2.696-699.1995.

The gene encoding protein D (hpd) is highly conserved among Haemophilus influenzae type b and nontypeable strains

X M Song  1 , A Forsgren, H Janson
Affiliations
Comparative Study

The gene encoding protein D (hpd) is highly conserved among Haemophilus influenzae type b and nontypeable strains

X M Song et al. Infect Immun. 1995 Feb.

Abstract

The molecular conservation of a surface-exposed lipoprotein, protein D, of Haemophilus influenzae was studied by cloning and sequencing of the gene encoding protein D from three encapsulated type b strains and three nontypeable strains of H. influenzae. These nucleotide sequences were analyzed with previously reported sequences from one type b strain and one nontypeable strain. The nucleotide sequences and the deduced amino acid sequences for protein D were highly conserved. The deduced amino acid sequence (364 amino acids) of protein D from six strains differed only in two amino acids near the C-terminal end. The remaining two strains, one type b and one nontypeable, differed from the consensus sequence in 7 amino acids each. Protein D is 64 and 36% identical and 77 and 56% similar to the glycerophosphodiester phosphodiesterases (GlpQ) of Escherichia coli and Bacillus subtilis.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Arch Intern Med. 1982 Mar;142(3):537-9 - PubMed
    1. J Bacteriol. 1990 Mar;172(3):1374-9 - PubMed
    1. J Clin Invest. 1983 Aug;72(2):677-84 - PubMed
    1. Nucleic Acids Res. 1984 Jan 11;12(1 Pt 1):387-95 - PubMed
    1. Infect Immun. 1985 Jan;47(1):253-9 - PubMed

Publication types

LinkOut - more resources