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Comparative Study
. 1994 Sep;32(9):2291-4.
doi: 10.1128/jcm.32.9.2291-2294.1994.

Standardized microtiter assay for determination of syncytium-inducing phenotypes of clinical human immunodeficiency virus type 1 isolates

A J Japour  1 , S A Fiscus, J M Arduino, D L Mayers, P S Reichelderfer, D R Kuritzkes
Affiliations
Comparative Study

Standardized microtiter assay for determination of syncytium-inducing phenotypes of clinical human immunodeficiency virus type 1 isolates

A J Japour et al. J Clin Microbiol. 1994 Sep.

Abstract

A standardized assay in 96-well microtiter plates for syncytium-inducing (SI) human immunodeficiency virus type 1 phenotype detection using MT-2 cells has been developed. SI variants were found in 67% of the patients with advanced human immunodeficiency virus disease. The occurrence of the SI phenotype increased with lower CD4+ counts. There was no association between p24 antigenemia and the SI phenotype.

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