Childhood NHL in Switzerland: incidence and survival of 120 study and 42 non-study patients
- PMID: 7700178
- DOI: 10.1002/mpo.2950240503
Childhood NHL in Switzerland: incidence and survival of 120 study and 42 non-study patients
Abstract
Based on the Swiss Pediatric Oncology Group (SPOG) cancer registry data during 1981-1991, a high average incidence of 8 new NHL per million children younger than 15 years per year was found. Of 162 children with NHL registered in 1976-1991, 120 were study patients, i.e., officially registered and treated according to SPOG or Pediatric Oncology Group (POG) protocols, while 42 were non-study patients, i.e., patients not officially enrolled on protocols. Overall, 91 of 120 (76%) study patients remained alive. Seventy-nine study patients were treated according to older SPOG protocols, and 53 (67%) of these survived, while 38 of 41 (93%) study patients treated according to newer POG protocols remained alive (P = 0.0068). Only 22 (52%) of the 42 non-study patients survived (P = 0.0001). There was no improvement if the survival of non-study patients before and since 1986 was compared. Population-based treatment results in Switzerland were similar to those in the United Kingdom. They provided an important base for the development of future treatment strategies.
Comment in
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The national impact of clinical cooperative group trials for pediatric cancer.Med Pediatr Oncol. 1995 May;24(5):279-80. doi: 10.1002/mpo.2950240502. Med Pediatr Oncol. 1995. PMID: 7700177 No abstract available.
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