doi: 10.1093/glycob/3.2.131.
The vascular E-selectin binds to the leukocyte integrins CD11/CD18
Affiliations
- PMID: 7683936
- DOI: 10.1093/glycob/3.2.131
Item in Clipboard
The vascular E-selectin binds to the leukocyte integrins CD11/CD18
Glycobiology.
1993 Apr.
Abstract
Leukocyte adhesion involves at least three molecular families of adhesion proteins: the leukocyte integrins CD11/CD18, the intercellular adhesion molecules (ICAMs) and the carbohydrate-binding L-, E- and P-selectins. The intercellular adhesion molecules are well-known ligands for the CD11/CD18 integrins. We now show that E-selectin specifically binds to the sialyl Lex carbohydrate epitopes of leukocyte integrins. Thus, the different families of leukocyte adhesion molecules form an integrated adhesion network.
Similar articles
-
ICAM-2 and a peptide from its binding domain are efficient activators of leukocyte adhesion and integrin affinity.J Immunol. 1999 Jun 1;162(11):6613-20. J Immunol. 1999. PMID: 10352278
-
Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils.J Cell Biol. 1991 Oct;115(1):223-34. doi: 10.1083/jcb.115.1.223. J Cell Biol. 1991. PMID: 1717478 Free PMC article.
-
Circulating adhesion molecules in sarcoidosis.Clin Exp Immunol. 1994 May;96(2):335-8. doi: 10.1111/j.1365-2249.1994.tb06563.x. Clin Exp Immunol. 1994. PMID: 7514516 Free PMC article.
-
Endothelial cell interactions and integrins.New Horiz. 1993 Feb;1(1):37-51. New Horiz. 1993. PMID: 7922392 Review.
-
Leukocyte adhesion: CD11/CD18 integrins and intercellular adhesion molecules.Curr Opin Cell Biol. 1997 Oct;9(5):643-50. doi: 10.1016/s0955-0674(97)80117-2. Curr Opin Cell Biol. 1997. PMID: 9330867 Review.
Cited by
-
The adhesion cascade and anti-adhesion therapy: an overview.Springer Semin Immunopathol. 1995;16(4):359-78. doi: 10.1007/BF00196093. Springer Semin Immunopathol. 1995. PMID: 7570288 Review. No abstract available.
-
Pathobiology of neutrophil-epithelial interactions.Immunol Rev. 2016 Sep;273(1):94-111. doi: 10.1111/imr.12446. Immunol Rev. 2016. PMID: 27558330 Free PMC article. Review.
-
E-selectin ligands as mechanosensitive receptors on neutrophils in health and disease.Ann Biomed Eng. 2012 Apr;40(4):849-59. doi: 10.1007/s10439-011-0507-y. Epub 2012 Jan 24. Ann Biomed Eng. 2012. PMID: 22271244 Free PMC article. Review.
-
Analysis of glycoprotein E-selectin ligands on human and mouse marrow cells enriched for hematopoietic stem/progenitor cells.Blood. 2011 Aug 18;118(7):1774-83. doi: 10.1182/blood-2010-11-320705. Epub 2011 Jun 9. Blood. 2011. PMID: 21659548 Free PMC article.
-
C-type lectins from the nematode parasites Heligmosomoides polygyrus and Nippostrongylus brasiliensis.Parasitol Int. 2009 Dec;58(4):461-70. doi: 10.1016/j.parint.2009.08.011. Epub 2009 Sep 13. Parasitol Int. 2009. PMID: 19751847 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
