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• Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death.

  Xiao HD, Fuchs S, Campbell DJ, Lewis W, Dudley SC Jr, Kasi VS, Hoit BD, Keshelava G, Zhao H, Capecchi MR, Bernstein KE. Xiao HD, et al. Am J Pathol. 2004 Sep;165(3):1019-32. doi: 10.1016/S0002-9440(10)63363-9. Am J Pathol. 2004. PMID: 15331425 Free PMC article.
• Angiotensin-converting enzyme converts amyloid beta-protein 1-42 (Abeta(1-42)) to Abeta(1-40), and its inhibition enhances brain Abeta deposition.

  Zou K, Yamaguchi H, Akatsu H, Sakamoto T, Ko M, Mizoguchi K, Gong JS, Yu W, Yamamoto T, Kosaka K, Yanagisawa K, Michikawa M. Zou K, et al. J Neurosci. 2007 Aug 8;27(32):8628-35. doi: 10.1523/JNEUROSCI.1549-07.2007. J Neurosci. 2007. PMID: 17687040 Free PMC article.
• A role of matrix metalloproteinase-8 in atherosclerosis.

  Laxton RC, Hu Y, Duchene J, Zhang F, Zhang Z, Leung KY, Xiao Q, Scotland RS, Hodgkinson CP, Smith K, Willeit J, López-Otín C, Simpson IA, Kiechl S, Ahluwalia A, Xu Q, Ye S. Laxton RC, et al. Circ Res. 2009 Oct 23;105(9):921-9. doi: 10.1161/CIRCRESAHA.109.200279. Epub 2009 Sep 10. Circ Res. 2009. PMID: 19745165 Free PMC article.
• Renal Blood Flow Response to Angiotensin 1-7 versus Hypertonic Sodium Chloride 7.5% Administration after Acute Hemorrhagic Shock in Rats.

  Maleki M, Nematbakhsh M. Maleki M, et al. Int J Vasc Med. 2016;2016:6562017. doi: 10.1155/2016/6562017. Epub 2016 Mar 17. Int J Vasc Med. 2016. PMID: 27073699 Free PMC article.
• Characterization of the first non-insect invertebrate functional angiotensin-converting enzyme (ACE): leech TtACE resembles the N-domain of mammalian ACE.

  Rivière G, Michaud A, Deloffre L, Vandenbulcke F, Levoye A, Breton C, Corvol P, Salzet M, Vieau D. Rivière G, et al. Biochem J. 2004 Sep 1;382(Pt 2):565-73. doi: 10.1042/BJ20040522. Biochem J. 2004. PMID: 15175004 Free PMC article.