Two independent pathways of expression lead to self-assembly of the rabbit hemorrhagic disease virus capsid protein
- PMID: 7637026
- PMCID: PMC189447
- DOI: 10.1128/JVI.69.9.5812-5815.1995
Two independent pathways of expression lead to self-assembly of the rabbit hemorrhagic disease virus capsid protein
Abstract
The rabbit hemorrhagic disease virus capsid protein was expressed in insect cells either as an individual protein species, from a mRNA analogous to the viral subgenomic RNA, or as part of a polyprotein that included the viral 3C-like protease and the RNA polymerase. Both pathways of expression led to the assembly of viruslike particles morphologically and antigenically similar to purified virus.
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