The homogeneity and monocytic origin of human peritoneal macrophages evidence by comparison of esterase polymorphism

Comparative Study

. 1981 Feb;102(2):209-18.

The homogeneity and monocytic origin of human peritoneal macrophages evidence by comparison of esterase polymorphism

M R Parwaresch, H J Radzun, M Dommes

PMID: 7468767
PMCID: PMC1903679

Comparative Study

The homogeneity and monocytic origin of human peritoneal macrophages evidence by comparison of esterase polymorphism

M R Parwaresch et al. Am J Pathol. 1981 Feb.

. 1981 Feb;102(2):209-18.

Authors

M R Parwaresch, H J Radzun, M Dommes

PMID: 7468767
PMCID: PMC1903679

Abstract

The aim of this study was to test the hypothesis of the homogeneity and monocytic origin of the normal unstimulated (resident) peritoneal macrophages in man. The isoelectric focusing pattern of one of the lysosomal marker enzymes, acid esterase (EC 3.1.1.6), was studied in highly purified samples of normal human blood cell fractions. All types of blood cells showed a cell-specific constellation of their enzyme variants as far as blood cells were concerned. Comparisons were made with resident peritoneal macrophages of healthy subjects. Only blood monocytes shared all their isoenzymes with peritoneal macrophages. Two additional bands, not seen in monocytes, occurred, however, in peritoneal macrophages. During exposure of blood monocytes to prolonged glass adherence there was a gradual transition of the monocytic pattern into that of peritoneal macrophages. The results document the homogeneity and monocytic origin of resident peritoneal macrophages in man.

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References

1. Arch Intern Med. 1971 Jun;127(6):1064-8 - PubMed
1. J Exp Med. 1978 Dec 1;148(6):1449-57 - PubMed
1. Blood. 1979 Aug;54(2):485-500 - PubMed
1. Cell Immunol. 1979 Jul;45(2):437-45 - PubMed
1. Clin Chim Acta. 1980 Mar 28;102(2-3):227-35 - PubMed

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[1] Arch Intern Med. 1971 Jun;127(6):1064-8 - PubMed

[2] Arch Intern Med. 1971 Jun;127(6):1064-8 - PubMed

[3] J Exp Med. 1978 Dec 1;148(6):1449-57 - PubMed

[4] J Exp Med. 1978 Dec 1;148(6):1449-57 - PubMed

[5] Blood. 1979 Aug;54(2):485-500 - PubMed

[6] Blood. 1979 Aug;54(2):485-500 - PubMed

[7] Cell Immunol. 1979 Jul;45(2):437-45 - PubMed

[8] Cell Immunol. 1979 Jul;45(2):437-45 - PubMed

[9] Clin Chim Acta. 1980 Mar 28;102(2-3):227-35 - PubMed

[10] Clin Chim Acta. 1980 Mar 28;102(2-3):227-35 - PubMed

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The homogeneity and monocytic origin of human peritoneal macrophages evidence by comparison of esterase polymorphism

The homogeneity and monocytic origin of human peritoneal macrophages evidence by comparison of esterase polymorphism

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