Comparative Study
doi: 10.1016/s0140-6736(78)90616-5.
Persistence of drug-resistant malaria parasites
- PMID: 74609
- DOI: 10.1016/s0140-6736(78)90616-5
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Comparative Study
Persistence of drug-resistant malaria parasites
Lancet.
.
Abstract
Mixtures of drug-resistant and sensitive forms of Plasmodium chabaudi were used to infect mice, and the resulting infections were maintained in the absence of drug. Both chloroquine-resistant and pyrimethamine-resistant mutans were able to survive in such mixed infections. The results of experiments on chloroquine resistance indicated an apparent selective advantage of the resistant over the sensitive form.
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