doi: 10.1007/BF02013227.
Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age
- PMID: 737547
- DOI: 10.1007/BF02013227
Item in Clipboard
Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age
Calcif Tissue Res.
.
Abstract
The mean wall thickness (MWT) of packets of trabecular bone was measured in undecalcified iliac crest bone samples of 36 normal subjects (14 female and 22 male) under polarized light. The mean wall thickness was 49.7 +/- 8.7 microns at a mean age of 50.9 years. There existed a significant decrease of MWT with advancing age. With an appositional rate of 0.72 micron/day, the mean formation time of iliac trabecular bone packets is 69 days. The decrease of MWT with age corresponds to a decrease in bone formation at the basic multicellular unit (BMU) level with aging and can partly explain the physiological senile osteopenia.
Similar articles
-
Mean wall thickness and formation periods of trabecular bone packets in corticosteroid-induced osteoporosis.Calcif Tissue Int. 1983 Jul;35(4-5):410-7. doi: 10.1007/BF02405069. Calcif Tissue Int. 1983. PMID: 6616314
-
Mean wall thickness and formation periods of trabecular bone packets in idiopathic osteoporosis.Calcif Tissue Int. 1981;33(3):199-204. doi: 10.1007/BF02409438. Calcif Tissue Int. 1981. PMID: 6791782
-
[A histomorphometric study of normal iliac trabecular bones. Part II: Age changes and the values of MWT and related parameters].Nihon Seikeigeka Gakkai Zasshi. 1988 Nov;62(11):943-9. Nihon Seikeigeka Gakkai Zasshi. 1988. PMID: 3249091 Japanese.
-
Effects of thyroid hormone(s) on mean wall thickness of trabecular bone packets.Metab Bone Dis Relat Res. 1981;3(3):181-5. doi: 10.1016/0221-8747(81)90006-0. Metab Bone Dis Relat Res. 1981. PMID: 7347794
-
Histomorphometric approach of bone loss in men.Calcif Tissue Int. 2001 Oct;69(4):209-13. doi: 10.1007/s00223-001-1047-5. Calcif Tissue Int. 2001. PMID: 11730252 Review.
Cited by
-
Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice.J Bone Miner Res. 2016 Dec;31(12):2215-2226. doi: 10.1002/jbmr.2900. Epub 2016 Sep 7. J Bone Miner Res. 2016. PMID: 27357062 Free PMC article.
-
Sclerostin is expressed in osteoclasts from aged mice and reduces osteoclast-mediated stimulation of mineralization.J Cell Biochem. 2013 Aug;114(8):1901-1907. doi: 10.1002/jcb.24537. J Cell Biochem. 2013. PMID: 23494985 Free PMC article.
-
Bone quality: the material and structural basis of bone strength.J Bone Miner Metab. 2008;26(1):1-8. doi: 10.1007/s00774-007-0793-5. Epub 2008 Jan 10. J Bone Miner Metab. 2008. PMID: 18095057 Review.
-
Bone loss in the elderly.Osteoporos Int. 1994;4 Suppl 1:59-65. doi: 10.1007/BF01623438. Osteoporos Int. 1994. PMID: 8081062 Review.
-
Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence.J Clin Invest. 1996 Apr 1;97(7):1732-40. doi: 10.1172/JCI118600. J Clin Invest. 1996. PMID: 8601639 Free PMC article.
References
MeSH terms
LinkOut - more resources
Other Literature Sources