doi: 10.1128/jb.144.2.852-855.1980.
Transposed LEU2 gene of Saccharomyces cerevisiae is regulated normally
- PMID: 7000755
- PMCID: PMC294742
- DOI: 10.1128/jb.144.2.852-855.1980
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Transposed LEU2 gene of Saccharomyces cerevisiae is regulated normally
J Bacteriol.
1980 Nov.
Abstract
The repression of beta-isopropylmalate dehydrogenase, the LEU2 gene product, by leucine and leucine plus threonine was unaffected by the transposition of LEU2 from its original locus on chromosome III to a new locus within the ribosomal deoxyribonucleic acid gene cluster on chromosome XII. Since the expression of the LEU2 gene is probably controlled at a pretranslational level, we conclude that the recombinant plasmid used for transformation carries regulatory information in addition to LEU2 structural information.
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