Two populations of Ia-like molecules on a human B cell line
- PMID: 6966655
Item in Clipboard
Two populations of Ia-like molecules on a human B cell line
J Immunol.
1980 Jul.
Abstract
Evidence is presented for two populations of Ia-like molecules on the human B cell line Raji. Two monoclonal antibodies, L203 and L227, are described. Both recognize nonpolymorphic determinants on B cell antigens. Both immunoprecipitate 34,000- and 28,000-dalton material from 125I-labeled extracts of Raji, but L227 precipitates 25,000-dalton material as well. Immunodepletion experiments confirm that the antibodies react with two different populations of molecules.
Similar articles
-
Analysis of HLA-DR antigens by using monoclonal antibodies: recognition of conformational differences in biosynthetic intermediates.J Immunol. 1981 Oct;127(4):1403-10. J Immunol. 1981. PMID: 6944380
-
Cross-reactions between mouse Ia and human HLA-D/DR antigens analyzed with monoclonal alloantibodies.J Immunol. 1981 Jun;126(6):2424-9. J Immunol. 1981. PMID: 6785353
-
HLA-DR epitope region definition by use of monoclonal antibody probes.J Immunol. 1980 Dec;125(6):2785-9. J Immunol. 1980. PMID: 6159421
-
Monoclonal antibodies to Ia antigens from rat thymus: cross reactions with mouse and human and use in purification of rat Ia glycoproteins.Immunol Rev. 1979;47:117-37. doi: 10.1111/j.1600-065x.1979.tb00291.x. Immunol Rev. 1979. PMID: 398324 Review. No abstract available.
-
Antigen-binding myeloma cells: monoclonal models of B cell differentiation.Prog Clin Biol Res. 1980;42:325-44. Prog Clin Biol Res. 1980. PMID: 6994115 Review. No abstract available.
Cited by
-
Approach for Identifying Human Leukocyte Antigen (HLA)-DR Bound Peptides from Scarce Clinical Samples.Mol Cell Proteomics. 2016 Sep;15(9):3017-29. doi: 10.1074/mcp.M116.060764. Epub 2016 Jul 24. Mol Cell Proteomics. 2016. PMID: 27452731 Free PMC article.
-
Morphologic and immunophenotypic heterogeneity of corneal dendritic cells.Graefes Arch Clin Exp Ophthalmol. 1991;229(2):182-5. doi: 10.1007/BF00170554. Graefes Arch Clin Exp Ophthalmol. 1991. PMID: 2044982
-
Structural organization of the DR subregion of the human major histocompatibility complex.Proc Natl Acad Sci U S A. 1985 Aug;82(15):5165-9. doi: 10.1073/pnas.82.15.5165. Proc Natl Acad Sci U S A. 1985. PMID: 3860851 Free PMC article.
-
Expression of major histocompatibility complex class I and class II antigens in human Schwann cell cultures and effects of infection with Mycobacterium leprae.Clin Exp Immunol. 1987 Jun;68(3):500-9. Clin Exp Immunol. 1987. PMID: 3115648 Free PMC article.
-
Selective and non-selective loss of immunoregulatory molecules (HLA-A,B,C antigens and LFA-3) in transitional cell carcinoma.Br J Cancer. 1990 Oct;62(4):603-6. doi: 10.1038/bjc.1990.338. Br J Cancer. 1990. PMID: 1699592 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources
Research Materials