doi: 10.1038/300330a0.
The sequences of an expressed rat alpha-tubulin gene and a pseudogene with an inserted repetitive element
- PMID: 6927856
- DOI: 10.1038/300330a0
Item in Clipboard
The sequences of an expressed rat alpha-tubulin gene and a pseudogene with an inserted repetitive element
Nature.
.
Abstract
The rat genome contains two segments closely related to a rat alpha-tubulin mRNA. Both have been cloned and complete nucleotide sequences are presented. Analysis of the structure and sequence of one of these establishes it as a functional alpha-tubulin gene. The second segment is a processed alpha-tubulin pseudogene. Comparison of this pseudogene to the mRNA and gene coding for alpha-tubulin strongly suggests that a mature mRNA was involved in its origin. Features of the pseudogene and a dispersed repetitive element inserted within it possibly reflect a common RNA-mediated process of insertion.
Similar articles
-
Tubulin genes are tandemly linked and clustered in the genome of trypanosoma brucei.Cell. 1983 Jan;32(1):35-43. doi: 10.1016/0092-8674(83)90494-4. Cell. 1983. PMID: 6825172
-
Cloning and characterization of a Leishmania gene encoding a RNA spliced leader sequence.Nucleic Acids Res. 1986 Sep 25;14(18):7341-60. doi: 10.1093/nar/14.18.7341. Nucleic Acids Res. 1986. PMID: 2429261 Free PMC article.
-
Structural features and restricted expression of a human alpha-tubulin gene.Nucleic Acids Res. 1985 Jan 11;13(1):207-23. doi: 10.1093/nar/13.1.207. Nucleic Acids Res. 1985. PMID: 3839072 Free PMC article.
-
Characterization of RNA transcripts from the alpha tubulin gene cluster of Leptomonas seymouri.Nucleic Acids Res. 1988 Apr 25;16(8):3455-69. doi: 10.1093/nar/16.8.3455. Nucleic Acids Res. 1988. PMID: 3131738 Free PMC article.
-
Repetitive nucleotide sequence insertions into a novel calmodulin-related gene and its processed pseudogene.Gene. 1988 Nov 15;71(1):123-34. doi: 10.1016/0378-1119(88)90084-4. Gene. 1988. PMID: 2463956
Cited by
-
A survey of the alpha-tubulin gene family in chicken: unexpected sequence heterogeneity in the polypeptides encoded by five expressed genes.EMBO J. 1988 Apr;7(4):931-40. doi: 10.1002/j.1460-2075.1988.tb02898.x. EMBO J. 1988. PMID: 3267229 Free PMC article.
-
Insertion of long interspersed repeated elements at the Igh (immunoglobulin heavy chain) and Mlvi-2 (Moloney leukemia virus integration 2) loci of rats.Proc Natl Acad Sci U S A. 1985 May;82(9):2857-61. doi: 10.1073/pnas.82.9.2857. Proc Natl Acad Sci U S A. 1985. PMID: 2986141 Free PMC article.
-
A multigene family of intron lacking and containing genes, encoding for mouse ribosomal protein L7.Nucleic Acids Res. 1984 May 11;12(9):3763-76. doi: 10.1093/nar/12.9.3763. Nucleic Acids Res. 1984. PMID: 6328436 Free PMC article.
-
A processed chicken pseudogene (CPS1) related to the ras oncogene superfamily.Nucleic Acids Res. 1986 Mar 11;14(5):2123-38. doi: 10.1093/nar/14.5.2123. Nucleic Acids Res. 1986. PMID: 3083400 Free PMC article.
-
The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3' termini.Nucleic Acids Res. 1985 Feb 25;13(4):1347-68. doi: 10.1093/nar/13.4.1347. Nucleic Acids Res. 1985. PMID: 2987822 Free PMC article.
Publication types
MeSH terms
Substances
Associated data
- Actions
- Actions
- Actions
Grants and funding
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
