doi: 10.1007/BF01971484.
Muscarinic cholinergic receptor binding in rat mast cells
- PMID: 6613746
- DOI: 10.1007/BF01971484
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Muscarinic cholinergic receptor binding in rat mast cells
Agents Actions.
1983 Jun.
Abstract
Specific [3H]-QNB binding was present in isolated, purified, intact rat mast cells and in crude membrane preparations. The binding is saturable, time- and temperature-dependent. Cholinergic agents inhibit selectively the binding: atropine is the most effective of the antagonists while oxotremorine is the most potent of the muscarinic agonists. It is concluded that rat mast cells are provided with muscarinic cholinergic receptors.
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