Analysis of the distribution of charged residues in the N-terminal region of signal sequences: implications for protein export in prokaryotic and eukaryotic cells
- PMID: 6499832
- PMCID: PMC557686
- DOI: 10.1002/j.1460-2075.1984.tb02132.x
Analysis of the distribution of charged residues in the N-terminal region of signal sequences: implications for protein export in prokaryotic and eukaryotic cells
Abstract
A statistical analysis of the distribution of charged residues in the N-terminal region of 39 prokaryotic and 134 eukaryotic signal sequences reveals a remarkable similarity between the two samples, both in terms of net charge and in terms of the position of charged residues within the N-terminal region, and suggests that the formyl group on Metf is not removed in prokaryotic signal sequences.
Similar articles
-
Net N-C charge imbalance may be important for signal sequence function in bacteria.J Mol Biol. 1986 Nov 20;192(2):287-90. doi: 10.1016/0022-2836(86)90365-7. J Mol Biol. 1986. PMID: 3560218
-
Membrane translocation of proteins without hydrophobic signal peptides.Curr Opin Cell Biol. 1990 Aug;2(4):617-24. doi: 10.1016/0955-0674(90)90102-k. Curr Opin Cell Biol. 1990. PMID: 2252588 Review. No abstract available.
-
Signal sequences. The limits of variation.J Mol Biol. 1985 Jul 5;184(1):99-105. doi: 10.1016/0022-2836(85)90046-4. J Mol Biol. 1985. PMID: 4032478
-
How signal sequences maintain cleavage specificity.J Mol Biol. 1984 Feb 25;173(2):243-51. doi: 10.1016/0022-2836(84)90192-x. J Mol Biol. 1984. PMID: 6423828
-
Homologies between sugar transporters from eukaryotes and prokaryotes.Annu Rev Physiol. 1989;51:459-71. doi: 10.1146/annurev.ph.51.030189.002331. Annu Rev Physiol. 1989. PMID: 2540699 Review. No abstract available.
Cited by
-
A plant signal sequence enhances the secretion of bacterial ChiA in transgenic tobacco.Plant Mol Biol. 1992 Jan;18(1):47-53. doi: 10.1007/BF00018455. Plant Mol Biol. 1992. PMID: 1731977
-
The cytoplasmic domain of Escherichia coli leader peptidase is a "translocation poison" sequence.Proc Natl Acad Sci U S A. 1988 May;85(10):3363-6. doi: 10.1073/pnas.85.10.3363. Proc Natl Acad Sci U S A. 1988. PMID: 3285342 Free PMC article.
-
Sequence analysis of cDNA coding for a major house dust mite allergen, Der p 1. Homology with cysteine proteases.J Exp Med. 1988 Jan 1;167(1):175-82. doi: 10.1084/jem.167.1.175. J Exp Med. 1988. PMID: 3335830 Free PMC article.
-
A novel wheat alpha-amylase gene (alpha-Amy3).Mol Gen Genet. 1987 Aug;209(1):33-40. doi: 10.1007/BF00329833. Mol Gen Genet. 1987. PMID: 17186618
-
A γ-hordein gene.Plant Mol Biol. 1988 Jul;11(4):449-61. doi: 10.1007/BF00039026. Plant Mol Biol. 1988. PMID: 24272402
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources