Comparative Study
doi: 10.1016/0378-1119(83)90203-2.
DNA sequence of the Herpes simplex virus type 2 glycoprotein D gene
- PMID: 6323270
- DOI: 10.1016/0378-1119(83)90203-2
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Comparative Study
DNA sequence of the Herpes simplex virus type 2 glycoprotein D gene
Gene.
1983 Dec.
Abstract
We describe a 1635-bp Herpes simplex virus type 2 (HSV-2) DNA sequence containing the entire coding region of glycoprotein D (gD-2). The amino acid sequence of gD-2, deduced from the nucleotide sequence, was compared to that of the analogous Herpes simplex virus type 1 (HSV-1) glycoprotein (gD-1). The two glycoproteins are 85% homologous and contain highly conserved regions of as much as 49 amino acids in length. Comparison of DNA sequences upstream from gD-1 and gD-2 coding regions identified possible conserved regulatory sequences.
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